- The Squire Animus has a level requirement of 60. However, this is increased to level 74 for items of Mythical Quality.
- As of PC patch 7.16c, Animi are now 7x more effective on Nightmare Difficulty.
Other animi are unlocked by defeating the Ancient Dragon in The Summit on at least Insane Difficulty while playing other hero classes. Note that these familiars can only be equipped by their corresponding hero class (e.g. an Apprentice or Adept can only equip the Apprentice Animus).
- Apprentice / Adept - Apprentice Animus
- Huntress / Ranger - Huntress Animus
- Monk / Initiate - Monk Animus